Our Product Pipeline
Our DiversImmune® and MultiMab platforms and licensing strategy have generated a pipeline of next-generation antibody product candidates, for which we have exclusive majority or full commercialization rights.
ABP 321: COVID-19 neutralizing monoclonal antibody for Pre-exposure Prophylaxis(PrEP)
Abpro is fast-tracking ABP-321, a human recombinant mAb of IgG1 type that binds to RBD in the S1 domain, neutralizing the virus and protecting hosting cells. Using a single B cell approach, diverse antibodies are isolated from donors who recently recovered from COVID-19 or received COVID-19 vaccination. ABP-321 targets PrEP for immunocompromised adults at risk of SARS-CoV2, with potent neutralization against all past and current major variants.
ABP 100: Bispecific antibody for breast/gastric/colorectal cancer
We have created a bispecific antibody to treat patients affected by HER2+ types of cancer, including breast, gastric and colorectal. Our molecule is highly specific for HER2+ tumors, and brings natural immune t-cells to the tumor to reduce it.
ABP 150: Bispecific antibody for gastric cancer
This is an advanced antibody treatment for gastric cancer using bispecific, or two-pronged antibodies. One arm binds to a cancer marker specific for gastric tumors and the other binds to an immune cell to bring it into close proximity with the tumor cell.
ABP 201: Bispecific antibody for Wet AMD/Diabetic macular edema
This is our next-generation treatment for those afflicted with Wet AMD/DME. These are generally diseases that gradually cause blindness in patients. Our molecule, a bispecific antibody, has been engineered to improve the current VEGF therapies already being used to treat patients effectively. By using the latest in antibody engineering, the molecule can potentially improve efficacy and also durability for patients, leading to an overall higher quality of life.