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Dr. George Tsokos

Dr. George Tsokos, M.D., serves as Member of Scientific Advisory Board at Alliance for Lupus Research, Inc. and Kypha Inc. From 1987 to 2007, Dr. Tsokos was a member of the Uniformed Services/Walter Reed community where served in various positions including Vice Chair for Research in the Department of Medicine and Chief of the Department of Cell Injury. In 2007 he joined the Beth Israel Medical Center as Chief of Rheumatology and Harvard Medical School as Professor of Medicine. He has served various leadership positions including President of the Clinical Immunology Society and as member or chair of multiple federal study sections and editorial boards of scientific journals. He has served (or serves) as Consulting Editor of the Journal of Clinical Investigation, Editor of Autoimmunity, Academic Editor of PLOS One and Editor-in-Chief of Clinical Immunology. He has been elected to the Association of American Physicians, Fellow of the American Association for the Advancement of Sciences and Master of the American College of Physicians. Dr. Tsokos’ research focuses on the cellular and molecular pathogenesis of systemic lupus erythematosus (SLE). His laboratory has opened and led the field of molecular abnormalities on immune cells in patients with SLE. He has identified several molecular abnormalities, including aberrant expression of CD3 zeta chain, cAMP response element modulator, calcium-calmodulin kinase IV and protein phosphatase 2A and demonstrated that when their expression is corrected in cells obtained from patients with SLE with either gene transfer or small molecule drugs the effector cell function returns to normal levels. He has constructed a series of novel mice to demonstrate in vivo the importance of the molecules expressed aberrantly in SLE T cells in the expression of autoimmunity and organ damage. Dr. Tsokos has trained over 100 colleagues many of whom hold senior leadership positions and run independent laboratories and has published more than 450 articles. His research is funded by NIH and DoD grants. Dr. Tsokos received his Medical Degree and a Doctorate in Sciences from the University of Athens. He trained in Internal Medicine at the University of Athens and Georgetown University/VA Medical Center in Washington DC and completed Immunology and Rheumatology Fellowships at the National Institutes of Health.

https://en.wikipedia.org/wiki/George_Tsokos
https://www.bidmc.org/research/research-by-department/medicine/rheumatology/tsokos-lab

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